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Friday, December 23, 2016

Maternal Flu: No Association with Autism

At JAMA Pediatrics, Ousseny Zerbo have an article titled "Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder."
Question Is there an association between maternal influenza infection and vaccination and autism risk?
Findings In a cohort study of 196 929 children, of whom 3103 had austism spectrum disorder, maternal influenza infection during pregnancy was not associated with increased autism risk. There was a suggestion of increased risk of autism spectrum disorders among children whose mothers received an influenza vaccination during their first trimester, but the association was statistically insignificant after adjusting for multiple comparisons, indicating that the finding could be due to chance.
Meaning Our findings do not call for vaccine policy or practice changes but do suggest the need for additional studies.