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Showing posts with label medical research. Show all posts
Showing posts with label medical research. Show all posts

Wednesday, June 24, 2026

RFK: Still Antivax

In The Politics of Autism, I analyze the myth that vaccines cause autism. This bogus idea can hurt people by allowing diseases to spread   Examples include measles, COVID, flu, and polio.  A top antivaxxer is HHS Secretary RFK Jr. He is part of the "Disinformation Dozen." He helped cause a deadly 2019 measles outbreak in Samoa.

Washington Post editorial:
Robert F. Kennedy Jr. and his allies at the Department of Health and Human Services have quieted their efforts to restrict access to immunizations after realizing they were politically disastrous. But that doesn’t mean they stopped trying to undermine these lifesaving tools.

 In April, the Centers for Disease Control and Prevention halted the publication of a study showing that last year’s covid-19 shot cut the risk of emergency department visits and hospitalizations in half among healthy adults, even though the findings cleared the agency’s scientific review process. That’s because Jay Bhattacharya, the agency’s interim director, objected to the study’s methodology, which he called “crap” and “logistically ridiculous.”

One of the nation’s top medical journals disagrees with his assessment. This week, JAMA Network Open published the rejected study, which was peer-reviewed. The journal also published commentary by Natalie Dean, a public health professor at Emory University, who explained that the study’s design, which involved comparing the test results of vaccinated and unvaccinated people who seek medical care at hospitals, had been used for decades to measure the effectiveness of shots.

The point here is not that the methodology is flawless; Dean and other vaccine researchers readily admit that it’s imperfect. The problem is that the administration tried to bury scientific evidence that contradicted Kennedy’s criticisms of covid vaccines.

The drama is playing out just as Kennedy is actively defending anti-vaccine research that was retracted in April over concerns of “serious methodological flaws.” The paper, published in Toxicology Reports, purported to find that 75 percent of sudden infant death syndrome cases occurred within seven days of vaccination, but critics found potential research errors and argued that its author misused data to suggest causality, leading its publisher to take it down.
Last week, Kennedy sent a letter to the journal’s editor in chief, demanding a “full explanation” for that retraction. This, Kennedy claimed in a social media post, would help “restore trust in public health by insisting on transparency, accountability, and open scientific inquiry — not by asking the public to accept decisions behind closed doors.”

That’s ironic, given that Kennedy and his underlings are attempting to reshape federal vaccine guidelines behind the scenes. The Post’s Rachel Roubein and Lena H. Sun report that researchers at the National Institutes of Health are being pushed to conduct research on vaccine injuries and alternative vaccine schedules, as well as toying with a plan to create a new science office at the CDC that would report to political staff.

Despite these efforts, most Americans remain solidly in favor of vaccines. But the growing case numbers of vaccine-preventable diseases show it doesn’t take many skeptics to weaken their effectiveness

Sunday, June 14, 2026

Retraction Update

In The Politics of Autism, I analyze the myth that vaccines cause autism. This bogus idea can hurt people by allowing diseases to spread   Examples include measles, COVID, flu, and polio.  A top antivaxxer is HHS Secretary RFK Jr. He is part of the "Disinformation Dozen." He helped cause a deadly 2019 measles outbreak in Samoa.

 Judy George at MedPage Today:

A 2010 paper that linked hepatitis B vaccines in infant boys to an increased risk of autism diagnosis was retracted and another study by the same authors is under investigation.

The study, published in the Journal of Toxicology and Environmental Health, Part A, claimed that boys vaccinated as neonates had a three times higher odds of an autism diagnosis compared with boys vaccinated after their first month of life or not at all.

The paper was included in a safety review of hepatitis B birth vaccination alongside work from David Geier and presented to the CDC's Advisory Committee on Immunization Practices at their meeting on December 4, the day before the committee voted to drop the agency's long-standing recommendation that every newborn receive a hepatitis B vaccine at birth.
...
The neonate paper was retracted because "concerns were raised regarding the methodology of the study and the reported conclusions," according to a notice from the journal's editor and publisher.

The journal contacted Gallagher and Goodman for an explanation and engaged an independent reviewer for a post-publication statistical review. The reviewer concluded that the study's conclusions were unsound "due to fundamental methodological flaws," leading the journal to retract the article. Gallagher and Goodman did not agree with the retraction.

The study had multiple flaws, noted David Mandell, ScD, of the University of Pennsylvania Perelman School of Medicine in Philadelphia, who was not involved in either the research or the journal's retraction decision.

These shortcomings led to "spurious findings based on a tiny group of children," said Mandell, a member of the Coalition of Autism Scientists, a group of autism researchers. "They speak to the need to radically reform the peer review process so that all science is reviewed with a keener eye."

Thursday, June 11, 2026

AMA v. RFK

In The Politics of Autism, I analyze the myth that vaccines cause autism. This bogus idea can hurt people by allowing diseases to spread   Examples include measles, COVID, flu, and polio.  A top antivaxxer is HHS Secretary RFK Jr. He is part of the "Disinformation Dozen." He helped cause a deadly 2019 measles outbreak in Samoa.

 Simon J. Levien at POLITICO:

American doctors want their leading lobby to drop its nice guy routine with Robert F. Kennedy Jr.

At the American Medical Association’s annual meeting this week, members of the group’s House of Delegates are sending a clear message to their leaders: Call out Kennedy, even if it costs us in the pocketbook.

That message was stated most clearly in the election of Sandra Fryhofer, an internist from Atlanta and uncompromising Kennedy critic, as AMA president-elect. She beat Michael Suk, who as AMA board chair in 2024 and 2025 prioritized doctors’ Medicare fees and promised continued pragmatism in dealing with Kennedy.


Fryhofer, who advised the vaccine committee whose members Kennedy fired last year, suggested that would be an abdication of doctors’ moral duty.

“Measles running rampant, public health destroyed, a trillion dollars ripped from Medicaid, inadequate physician payment, stupid immigration rules,” Fryhofer told AMA members in promising to call out Kennedy and the Trump administration on all of it.

In two dozen interviews this week, AMA doctors described an advocacy organization at its wit’s end with Kennedy. POLITICO granted them anonymity to describe internal dynamics. Long a Republican-leaning constituency, doctors began shifting left during the battles over managed care three decades ago. President Donald Trump’s alliance with Kennedy, a longtime skeptic of vaccine safety and critic of the medical establishment, was the last straw for many.

Wednesday, May 27, 2026

Study Finds No Link to Common Antidepressants


A release from The Lancet Psychiatry:
  • Meta-analysis of 37 studies totalling more than half a million pregnancies with antidepressant use found no significant link between common antidepressant use during pregnancy and autism/ADHD in children after adjusting for the mother’s mental health and other factors.
  • Before accounting for confounding factors, the study found a small association between antidepressant use during pregnancy and autism or ADHD in children. However, this link was also seen with antidepressant use in mothers before conception and in fathers during pregnancy, suggesting the association reflects parental mental health and genetics rather than the medication itself.
  • Authors say doctors and patients should weigh the benefit and risks of antidepressant use for moderate to severe depression in pregnancy with the potential harms of a depression relapse. They highlight that supporting good mental health for both mothers and fathers is beneficial for a child’s neurodevelopment.
Current evidence does not support a causal link between the use of almost all antidepressants during pregnancy and an increased risk of neurodevelopmental disorders, including autism and attention-deficit/hyperactivity disorder (ADHD), in children, according to a systematic review and meta-analysis published in The Lancet Psychiatry journal.

Previous meta-analyses looking at the use of antidepressants during pregnancy and risk of neurodevelopmental disorders in children were conducted nearly a decade ago and limited by small study numbers and a lack of controlling for additional factors. This new meta-analysis provides the best evidence to date that the small increase in risk of autism or ADHD in the children of women who used antidepressants when pregnant identified in many studies is not caused by the medication.




“We know many parents-to-be worry about the potential impact of taking medication during pregnancy; our study provides reassuring evidence that commonly used antidepressants do not increase the risk of neurodevelopmental disorders such as autism and ADHD in children. While all medications carry risks, so too does stopping antidepressants during pregnancy due to an increased risk of relapse. Therefore, for women with moderate-severe depression, doctors and patients must carefully weigh the potential risks and benefits of continuing antidepressant treatment during pregnancy against the potential harms of untreated depression,” says author Dr Wing-Chung Chang, University of Hong Kong.

He continues, “Although our study found a small increase in the risk of autism and ADHD in the children of women who had used antidepressants during pregnancy, it also found that this risk disappeared when we accounted for other factors. The increased risk was also seen in the children of fathers who took antidepressants and of mothers with antidepressant use before, but not during, pregnancy. Together, this suggests that it is not the antidepressants themselves causing an increased risk in autism and ADHD but it is more likely to be due to other factors, including genetic predisposition to conditions such as ADHD, autism, and mental health conditions.”

Authors pooled data from 37 studies which included more than 600,000 pregnant women taking antidepressants and almost 25 million pregnancies with no antidepressant use.

Before controlling for key factors such as mental health conditions, the analysis found that antidepressant use by the mother during pregnancy was associated with a 35% increased risk of ADHD and a 69% increased risk of autism. However, this became greatly reduced or non-significant in analyses that better controlled for confounding factors. Use of antidepressants during pregnancy by the father was associated with a 46% increase in the risk of ADHD and a 28% increase in the risk of autism.
Among studies with analyses restricted to mothers with mental health disorders, all selective serotonin reuptake inhibitors (SSRIs) were found to not be associated, only amitriptyline/nortriptyline remained associated with increased ADHD and autism risk. Amitriptyline/nortriptyline are currently considered second or third options as treatments for depression and are often prescribed for treatment-resistant depression. Therefore, women treated with these may have more severe, chronic, or complex underlying mental health conditions than those receiving more common antidepressants, which could be influencing the association between amitriptyline/nortriptyline and increased ADHD and autism risk.

The study found no difference in risk between high and low doses of antidepressants.

“The evidence suggests a link between either parent having a mental health condition and a slightly higher risk of ADHD or autism. In addition to genetic factors, this link could be explained by the home and social environment as ongoing family stress, changes in how the family functions, and differences in how parents behave and care for their children may influence neurodevelopment. There is a need to ensure both parents have access to support and treatment for mental health conditions; for their own sake and to support neurodevelopment of their child," says Dr. Joe Kwun-Nam Chan, University of Hong Kong.

The researchers note some limitations of their study, including that data on important factors such as socioeconomic status, lifestyle risk factors and low birth weight was lacking in the studies. Additionally, there was only a small number of studies looking at antidepressant use in specific trimesters or exact doses and dose changes, which makes it harder to draw conclusions about these. Finally, women who are prescribed antidepressants tend to have more severe depression than those who are not, so some bias may remain even after controlling for mental health status.

Writing in a linked Comment, Lisa Vitte, Emmanuel Devouche and Gisele Apter from University Rouen Normandy (France), who were not involved in the study, say, “Chang and colleagues’ study adds knowledge and confirms some of the pre-existing knowledge on the use of antidepressants during pregnancy: that they should continue to be taken as they protect maternal mental health and do not harm fetal development. This result is of considerable impact after many contradictory and controversial studies.

Thursday, May 14, 2026

Yet Another Potential Correlate: Maternal Occupation History

 In The Politics of Autism, I discuss various ideas about what causes the condition.  Dozens of potential causes and correlates have been the subject of scientific and medical research.

Abstract

Objectives We investigated associations between maternal occupations and a diagnosis of autism spectrum disorder (ASD) in offspring.

Methods We obtained data for 1702 ASD cases born between 1973 and 2012 from the Danish National Patient Registry and matched each case to up to 100 population based controls based on sex and birth year (n=110 234). Mothers’ employment histories were obtained from the Danish Pension Fund Registry. Conditional logistic regression models were used to test associations between occupations held ever, 1 year before conception, during pregnancy and during infancy, adjusting for the mother’s age and history of neuropsychiatric disorders, parity and residential location.

Results There were increased odds of having a child with ASD for mothers who were employed before conception up to infancy in ground transportation (adjusted OR (aOR) 1.24, 95% CI 1.08 to 1.42; q=0.036), public administration (aOR 1.20, 95% CI 1.07 to 1.35; q=0.018) and military/defence occupations (aOR 1.59, 95% CI 1.39 to 1.82; q<0.001). Associations for judicial occupations and military/defence service were also apparent 1 year before conception and during pregnancy. We observed sex differences, with significant associations in male children for employment in ground transportation and defence occupations.

Conclusions Associations between certain maternal employment categories with high toxicant or psychosocial stress exposure suggest future studies should focus on examining specific toxicant exposures common in those occupations and neurodevelopment in offspring. This is of particular concern for associations seen for occupations held several years before conception.
A partial list of other potential causes and correlates: 
  1. Inflammatory bowel disease
  2. Pesticides
  3. Air pollution and proximity to freeways
  4. Maternal thyroid issues
  5. Autoimmune disorders
  6. Induced labor
  7. Preterm birth
  8. Fever  
  9. Birth by cesarean section;
  10. Anesthesia during cesarean sections
  11. Maternal and paternal obesity
  12. Maternal diabetes
  13. Maternal and paternal age
  14. Grandparental age
  15. Maternal post-traumatic stress disorder
  16. Maternal anorexia
  17. Smoking during pregnancy
  18. Cannabis use during pregnancy
  19. Antidepressant use during pregnancy
  20. Polycystic ovary syndrome
  21. Infant opioid withdrawal
  22. Zinc deficiency
  23. Sulfate deficiency
  24. Processed foods
  25. Maternal occupational exposure to solvents
  26. Congenital heart disease
  27. Insufficient placental allopregnanolone
  28. Estrogen in the womb
  29. Morning sickness;
  30. Paternal family history
  31. Parental preterm birth
  32. Antiseizure meds
  33. Location of forebears
  34. Lithium
  35. Aspartame
  36. BPA
  37. Brain inflammation
  38. Maternal asthma
  39. Infertility
  40. Ultraprocessed foods
  41. Household chemicals
  42. Parental psychiatric disorders
  43. Fluoride
  44. Fatty acids in umbilical cord blood
  45. Maternal inflammation during pregnancy
  46. COVID-19
  47. Wildfire smoke
  48.  Sterol biosynthesis–inhibiting medications (SBIMs)

Sunday, May 10, 2026

Aluminum in Vaccines Not Linked to Autism

  In The Politics of Autism, I analyze the myth that vaccines cause autism. This bogus idea can hurt people by allowing diseases to spread   Examples include measlesCOVID, flu, and polio.  A top antivaxxer is HHS Secretary RFK JrHe is part of the "Disinformation Dozen." He helped cause a deadly 2019 measles outbreak in Samoa.

 Liz Szabo at CIDRAP:

Aluminum additives used in vaccines are not linked to serious medical problems or long-term conditions in children, according to a report published today in The BMJ. In particular, researchers found no increased risk of asthma, autism, or autoimmune conditions such as type 1 diabetes.

The analysis, which included 59 studies conducted over many years, adds to a large body of research finding no ties between aluminum in childhood vaccines and serious health problems, including a 24-year study of more than 1.2 million Danish children published last year in the Annals of Internal Medicine.

“The evidence shows that vaccines containing aluminum are safe,” said Joseline Zafack, MD, PhD, MPH, senior author of the study and an epidemiologist at the Centre for Immunization Surveillance and Programs at the Public Health Agency of Canada.
...
Anti-vaccine activists, including Health and Human Services Secretary Robert F. Kennedy Jr., have attacked the use of aluminum in vaccines for years.

Kennedy, an attorney who has made millions of dollars working with a law firm suing a vaccine manufacturer, last year called for the Annals of Internal Medicine to retract the 2025 Danish study that found no link between aluminum in vaccines and autism. The journal’s editors refused.

There’s no reason to suspect aluminum as a cause of autism, Hotez said.

“This is what they do,” Hotez said. “It’s just made up."

Dozens of studies have consistently found no link between vaccines and autism or other serious illnesses. But vaccines have saved more than 150 million lives over the past 50 years, according to the World Health Organization.

Tuesday, April 21, 2026

Sterol Biosynthesis–Inhibiting Medications (SBIMs)


A release from the University of Nebraska Medical Center:
A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in children.

Analyzing 6.14 million maternal-child health records from the Epic Cosmos database—representing nearly one-third of all U.S. births between 2014 and 2023—the team found that prescription of medications known to inhibit the cholesterol synthesis pathway were consistently associated with higher rates of ASD in offspring.

While previous studies grouped medications by their indications, the UNMC team grouped prescribed medications together based on common effects and side effects on sterol biosynthesis.

These sterol biosynthesis–inhibiting medications (SBIMs) include certain antidepressants, antipsychotics, anxiolytics, beta-blockers and statins. These are the generic names of the 14 medications studied: aripiprazole, atorvastatin, bupropion, buspirone, fluoxetine, haloperidol, metoprolol, nebivolol, pravastatin, propranolol, rosuvastatin, sertraline, simvastatin and trazodone. Many of these are among the most commonly prescribed medications in the United States, accounting for more than 400 million annual prescriptions.

... 

Publication details

Eric S. Peeples et al, Sterol pathway disruption in pregnancy: a link to autism, Molecular Psychiatry (2026). DOI: 10.1038/s41380-026-03610-7 Journal information: Molecular Psychiatry

A partial list of other potential causes and correlates: 

  1. Inflammatory bowel disease
  2. Pesticides
  3. Air pollution and proximity to freeways
  4. Maternal thyroid issues
  5. Autoimmune disorders
  6. Induced labor
  7. Preterm birth
  8. Fever  
  9. Birth by cesarean section;
  10. Anesthesia during cesarean sections
  11. Maternal and paternal obesity
  12. Maternal diabetes
  13. Maternal and paternal age
  14. Grandparental age
  15. Maternal post-traumatic stress disorder
  16. Maternal anorexia
  17. Smoking during pregnancy
  18. Cannabis use during pregnancy
  19. Antidepressant use during pregnancy
  20. Polycystic ovary syndrome
  21. Infant opioid withdrawal
  22. Zinc deficiency
  23. Sulfate deficiency
  24. Processed foods
  25. Maternal occupational exposure to solvents
  26. Congenital heart disease
  27. Insufficient placental allopregnanolone
  28. Estrogen in the womb
  29. Morning sickness;
  30. Paternal family history
  31. Parental preterm birth
  32. Antiseizure meds
  33. Location of forebears
  34. Lithium
  35. Aspartame
  36. BPA
  37. Brain inflammation
  38. Maternal asthma
  39. Infertility
  40. Ultraprocessed foods
  41. Household chemicals
  42. Parental psychiatric disorders
  43. Fluoride
  44. Fatty acids in umbilical cord blood
  45. Maternal inflammation during pregnancy
  46. COVID-19
  47. Wildfire smoke

 

Monday, March 30, 2026

Autism, Genetics, and Ancestry

  In The Politics of Autism, I discuss various ideas about what causes the conditionGenetics plays an important role

From Mount Sinai Hospital:

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ancestries. The findings, based on one of the largest genomic studies of Latin American individuals to date, provide strong evidence that the genetic architecture of autism is consistent across diverse populations. They underscore the importance of expanding genetic research beyond individuals of European ancestry.

Over the past decade, scientists have identified numerous rare genetic variants that confer substantial risk for autism and other neurodevelopmental disorders. However, most of these discoveries were made in cohorts composed predominantly of individuals of European ancestry, leaving open the question of whether autism's genetic underpinnings differ across populations. This knowledge gap has contributed to disparities in genetic testing, including higher rates of inconclusive results among non-European individuals due to limited reference data.

To address this issue, the research team analyzed exome and genome sequencing data from more than 15,000 Latin American individuals across North, Central, and South America, including approximately 4,700 individuals diagnosed with autism. Latin American populations represent the largest recent mixed-ancestry group globally, with heritage that frequently includes Indigenous American, West African, and European origins. This rich genetic diversity provides a powerful opportunity to refine gene-disease associations, which can improve health outcomes for all populations.

The study examined more than 18,000 genes for enrichment of rare, deleterious coding variants—genetic changes that can have immediate and profound clinical implications for diagnosis, treatment, and family counseling.

Consistent with prior research, rare, deleterious variants in highly conserved genes—genes that remain similar across species and populations over long periods of time—were disproportionately observed in individuals with autism. Researchers identified 35 genes significantly associated with autism in the Latin American cohort. These genes showed extensive overlap with those previously identified in genome-wide studies of individuals of European ancestry. The findings also provide support for several recently identified "emerging" autism-associated genes.

"Our results indicate that the core genetic architecture of autism is shared across ancestries," said study senior author Joseph D. Buxbaum, Ph.D., Director of the Seaver Autism Center for Research and Treatment at Mount Sinai. "This suggests that the biology underlying autism is universal and reinforces the importance of ensuring that diverse populations are represented in genetic research."

Thursday, March 12, 2026

Leucovorin Walkback

 number oposts discussed Trump's support for discredited notions about autism A September news conference was a firehose of lies.

Ariana Eunjung Cha and Rachel Roubein at WP:

Nearly six months ago, federal health officials gathered at the White House with President Donald Trump and vowed to “go bold” on autism. They sketched out plans for what they described as an “exciting treatment” for children with the condition — a decades-old drug, leucovorin, newly recast as a potential breakthrough.

“Hundreds of thousands of kids, in my opinion, will benefit,” Food and Drug Administration Commissioner Marty Makary said at the time.


But the administration is scaling back that vision. FDA announced Tuesday that it will expand approval for leucovorin, but only for a separate condition that some people with autism also have — not for autism itself.

...
“When we first started considering the ability to expand an indication for leucovorin, we did consider broadly whether there was data to support its use in a broader autism spectrum disorder population,” said a senior agency official.


But a systematic review of the literature led the agency to focus elsewhere. The “strongest data,” officials said, were concentrated among patients with the genetic form of cerebral folate deficiency, a condition they estimate affects “less than one in a million” people.
...


The initial press conference in September where Trump and his aides touted the prospect of expanding the drug’s use triggered immediate pushback. The president separately blamed Tylenol for causing autism — a claim without a proven link — and many in the medical establishment questioned the idea of prescribing leucovorin for a much broader population. Professional societies and individual physicians alike warned that the evidence base was thin.

A decades-old drug typically used alongside chemotherapy, leucovorin has been tested for autism-related symptoms in only a handful of small clinical trials in the United States and abroad. Some studies suggested modest gains in speech and behavior. But the data fell far short of the rigorous, large-scale evidence the FDA generally requires before granting approval for a new use.

The largest of the leucovorin-autism studies was retracted by the European Journal of Pediatrics on Jan. 29; after the authors acknowledged some errors, the editors wrote that the publication “no longer has confidence in the validity of the results and conclusions reported in this article.”

Monday, February 23, 2026

Preventing Autism?

  In The Politics of Autism, I discuss various ideas about what causes the conditionDozens of potential causes and correlates have been the subject of scientific and medical research.

Ariana Eunjung Cha at WP:

One peer-reviewed paper generating buzz in the autism research community published in December argues that a staggering number, more than half of autism cases, could be prevented with the right interventions. It proposes a “three-hit” theory suggesting that genetic susceptibility combined with environmental exposure and prolonged period of physiological stress contribute to autism.

Separately, two recent studies found that parents with the highest levels of an unusual sensitivity to everyday substances even at low levels, as measured by self-reported symptom patterns and validated questionnaires, were two times to 5.7 times more likely to report having a child with autism, prompting researchers to urge couples trying to conceive to minimize environmental exposures in their homes.\

...

In 2024, [Claudia] Miller and her colleagues published an analysis showing that in a group of nearly 8,000 U.S. adults, parents with chemical intolerance scores in the top 10th percentile were 5.7 times as likely to have a child with autism when compared with those in the bottom 10th percentile.

Those findings were replicated in a study published in January 2026 in the Journal of Xenobiotics, which examined children in five countries. In Italy, India and the United States, children born to parents with the highest levels of chemical intolerance had more than a twofold increased risk of autism; in Mexico, the risk was 1.9 times higher. No association was found in the Japanese data, though researchers suggested cultural differences in diagnosis and awareness may have influenced the results.

...

Helen Tager-Flusberg, director of Boston University’s Center for Autism Research Excellence and a founder of a coalition of autism scientists calling for more rigorous research, said there is little evidence that specific interventions during the preconception window could make a significant difference. She cautioned that focusing on this period is premature — and possibly harmful — given the current limits of the science. She pointed to the past, when both researchers and the public wrongly blamed so-called “refrigerator mothers” (who were cold or emotionally distant) and their parenting for autism.

“For decades now we’ve done too much as a society to make women feel the burden is on them,” she said.

She said the best advice for women considering pregnancy hasn’t changed for decades: take prenatal vitamins with folic acid, eat a healthy diet, stay fit, and avoid drugs, alcohol and smoking.


Thursday, February 12, 2026

No Link Between COVID Vaccine and Autism

In The Politics of Autism, I analyze the myth that vaccines cause autism. This bogus idea can hurt people by allowing diseases to spread   Examples include measlesCOVID, flu, and polio.  A top antivaxxer is HHS Secretary RFK JrHe is part of the "Disinformation Dozen." He helped cause a deadly 2019 measles outbreak in Samoa.


Liz Szabo at CIDRAP
A study today finds no increase in autism rates in babies born to mothers who received COVID-19 vaccines just before or during pregnancy, compared with children of unvaccinated moms.

The authors of the study, who presented their findings at the Society for Maternal-Fetal Medicine 2026 Pregnancy Meeting, told CIDRAP News they hope the research will help dispel myths about COVID-19 vaccines, which multiple studies have found to be safe and effective during pregnancy.

Half of the 434 children in the study, conducted at 14 medical facilities from May 2024 to March 2025, were born to mothers who received at least one dose of an mRNA vaccine during or within 30 days before pregnancy. The other half of the children in the study were born to mothers who weren’t vaccinated before or during pregnancy.

Researchers evaluated toddlers between the ages of 18 months and 30 months for signs of autism using four standard screenings: the Ages and Stages Questionnaire Version 3 (ASQ-3), the Child Behavior Checklist, the Modified Checklist for Autism in Toddlers, and the Early Childhood Behavior Questionnaire. None of these measures are used to make a definitive diagnosis of autism, but they can indicate a need for further testing.

When the researchers compared the scores on all four screening assessments, they found no significant differences between the children born to vaccinated mothers and those born to unvaccinated mothers.

“The fact that there were no differences on all four of these outcomes is evidence that COVID vaccination does not result in developmental concerns for most children,” said Alycia Halladay, PhD, chief science officer at the Autism Science Foundation, who was not involved in the new study. “For people who are worried that taking the COVID vaccine during pregnancy may cause autism, the study is pretty clear, convincing evidence that it does not.”

The authors of the study said its results are reassuring.

“We found no evidence in our study or in other studies that [the COVID] vaccine causes harm to the children,” said George R. Saade, MD, the new study’s first author and professor and chair of obstetrics and gynecology at Virginia Health Sciences at Old Dominion University.